“A key function of education is to produce workers for the economy, as such Industry 4.0 naturally has a profound impact on how education is being delivered and how teaching is done.” (Singapore Minister for Education Mr Ong Ye Kung). Education in the Fourth Industrial Revolution (Education 4.0) is a complex, dialectical and exciting opportunity which can potentially transform society for the better one. The fourth industrial revolution is powered by artificial intelligence (AI), even and it would revolutionise the workplace from tasks based characteristics to the human centred characteristics. Because of the convergence of man and machine, it would reduce the subject distance between humanities and social science as well as science and technology. Undoubtedly, this process would necessarily require much more practically interdisciplinary teaching, research and innovation. This paper explores the depth of Education 4.0 by analysing the possibilities, challenges and solutions based on the background of the Fourth Industrial Revolution. From that, the answer for the two main questions: (i) “What will make Education 4.0 possible ?” and (ii) “What should E 4.0 concentrate on?” would be made clear. As a result, the final version of possible E 4.0 would be one of the most suitable education trends for the new digital era.